National Institutes of Health Center for Translational Therapeutics
NCTT is now part of the NIH National Center for Advancing Translational Sciences (NCATS). Content on this site will move to NCATS.NIH.GOV

Translational Therapeutics Pipeline

Roll your mouse over the image to learn more about steps in the pipeline process.

Translational Therapeutics Pipeline Collaborator Inputs Disease Biology Unvalidated Target Validated Target Target Assay Lead Compound Preclinical Development Candidate Clinical Development Candidate Target Validation Assay Development Probe / Lead Development Lead Optimization Pre-clinical Development Clinical Trials What NCTT Does RNAi Probe Dev (MLP, CBC) TRND Assay Development BrIDGs-RAID Clinical TRND-FDA Collaboration TOX21 Systems Toxicology Program Repurposing Repurposing Paradigm/Technology Development Validated Targets HTS Assays Probes Lead Series Clinical Drug Candidates Human Proof of Concept Licensing and Commercialization Partners FDA Approval FDA Approved Drug Outcomes and Resources

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Updated: August 24, 2011