National Institutes of Health Center for Translational Therapeutics
NCTT is now part of the NIH National Center for Advancing Translational Sciences (NCATS). Content on this site will move to NCATS.NIH.GOV

Mission, Vision and Objectives

Mission

The mission of the National Institutes of Health Center for Translational Therapeutics (NCTT) is to translate fundamental research into patient treatments by establishing creative partnerships and developing innovative approaches to advance the science of drug discovery.

Vision

Our vision is to be a pioneer in drug discovery research, developing new paradigms to transform the drug development process and exploring treatments to improve the lives of every person suffering from illness or disease.

Strategic Objectives

  • Develop new paradigms, systems, and technologies across the translational spectrum to improve the speed, cost, and success rate of drug development
  • Discover, develop, and disseminate research tools and products to expand therapeutic genome space
  • Foster collaborations among scientists within NCTT and with outside collaborators to facilitate drug research and development
  • Educate stakeholders on NCTT's capabilities and the drug development process by providing knowledge and expertise on the necessary steps to translate research discoveries to therapeutics

About NCTT

NCTT researchers are equipped with diverse and unique scientific expertise to develop tools and technologies to translate biological insights into functional and therapeutic innovations. NCTT supports exploratory, discovery and development projects along the drug development pipeline.

This includes:
  • Discovering and validating disease pathways and targets.
  • Developing functional screening assays.
  • Conducting quantitative high through-put small molecule and known drug screening.
  • Conducting analytical and medicinal chemistry.
  • Solving structure-activity relationships.
  • Supporting pre-clinical and early clinical efficacy and toxicity research.
  • Facilitating regulatory review and initial clinical trials.
  • Conducting technology development and innovative approaches in biology, chemistry, informatics, regulatory paths, clinical trials, and research support (technology transfer, collaborative agreements/awards, contracting mechanisms, and strategic alliances).

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    Last Updated: July 12, 2011